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Tumor and Stem Cell Biology

Keratin-17 Promotes p27KIP1 Nuclear Export and Degradation and Offers Potential Prognostic Utility

Luisa F. Escobar-Hoyos, Ruchi Shah, Lucia Roa-Peña, Elizabeth A. Vanner, Nilofar Najafian, Anna Banach, Erik Nielsen, Ramsey Al-Khalil, Ali Akalin, David Talmage and Kenneth R. Shroyer
Luisa F. Escobar-Hoyos
1Department of Pharmacological Sciences, Stony Brook Medicine, Stony Brook, New York.
2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
3Department of Biology, Research Group Genetic Toxicology and Cytogenetics, Department of Natural Sciences and Education, Universidad del Cauca, Popayán, Cauca, Colombia.
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Ruchi Shah
2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
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Lucia Roa-Peña
2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
4Department of Pathology, School of Medicine, National University of Colombia, Bogotá, Cundinamarca, Colombia.
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Elizabeth A. Vanner
2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
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Nilofar Najafian
2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
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Anna Banach
5Molecular and Cellular Biology, Stony Brook Medicine, Stony Brook, New York.
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Erik Nielsen
2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
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Ramsey Al-Khalil
2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
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Ali Akalin
6Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, Massachusetts.
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David Talmage
1Department of Pharmacological Sciences, Stony Brook Medicine, Stony Brook, New York.
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Kenneth R. Shroyer
2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
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  • For correspondence: kenneth.shroyer@stonybrookmedicine.edu
DOI: 10.1158/0008-5472.CAN-15-0293
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ARTICLE USAGE: June 2015 to January 2021

AbstractFull-text HTMLPDF
Total586334352685

Cited By

Article Information

DOI 
https://doi.org/10.1158/0008-5472.CAN-15-0293
PubMed 
26109559

Published By 
American Association for Cancer Research
Print ISSN 
0008-5472
Online ISSN 
1538-7445
History 
  • Received January 28, 2015
  • Revision received April 29, 2015
  • Accepted May 14, 2015
  • Published first June 24, 2015.

Copyright & Usage 
©2015 American Association for Cancer Research.

Author Information

  1. Luisa F. Escobar-Hoyos1,2,3,
  2. Ruchi Shah2,
  3. Lucia Roa-Peña2,4,
  4. Elizabeth A. Vanner2,
  5. Nilofar Najafian2,
  6. Anna Banach5,
  7. Erik Nielsen2,
  8. Ramsey Al-Khalil2,
  9. Ali Akalin6,
  10. David Talmage1, and
  11. Kenneth R. Shroyer2,*
  1. 1Department of Pharmacological Sciences, Stony Brook Medicine, Stony Brook, New York.
  2. 2Department of Pathology, Stony Brook Medicine, Stony Brook, New York.
  3. 3Department of Biology, Research Group Genetic Toxicology and Cytogenetics, Department of Natural Sciences and Education, Universidad del Cauca, Popayán, Cauca, Colombia.
  4. 4Department of Pathology, School of Medicine, National University of Colombia, Bogotá, Cundinamarca, Colombia.
  5. 5Molecular and Cellular Biology, Stony Brook Medicine, Stony Brook, New York.
  6. 6Department of Pathology, University of Massachusetts Memorial Medical Center, Worcester, Massachusetts.
  1. ↵*Corresponding Author:
    Kenneth R. Shroyer, Department of Pathology, Basic Science Tower, Level 9, Stony Brook Medicine, Stony Brook, NY 11794. Phone: 631-444-3000; Fax: 631-444-3424; E-mail: kenneth.shroyer{at}stonybrookmedicine.edu
  1. R. Shah and L. Roa-Peña contributed equally to this article.

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doi: 10.1158/0008-5472.CAN-15-0293

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Keratin-17 Promotes p27KIP1 Nuclear Export and Degradation and Offers Potential Prognostic Utility
Luisa F. Escobar-Hoyos, Ruchi Shah, Lucia Roa-Peña, Elizabeth A. Vanner, Nilofar Najafian, Anna Banach, Erik Nielsen, Ramsey Al-Khalil, Ali Akalin, David Talmage and Kenneth R. Shroyer
Cancer Res August 18 2015 DOI: 10.1158/0008-5472.CAN-15-0293

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Keratin-17 Promotes p27KIP1 Nuclear Export and Degradation and Offers Potential Prognostic Utility
Luisa F. Escobar-Hoyos, Ruchi Shah, Lucia Roa-Peña, Elizabeth A. Vanner, Nilofar Najafian, Anna Banach, Erik Nielsen, Ramsey Al-Khalil, Ali Akalin, David Talmage and Kenneth R. Shroyer
Cancer Res August 18 2015 DOI: 10.1158/0008-5472.CAN-15-0293
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Cancer Research Online ISSN: 1538-7445
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