PT - JOURNAL ARTICLE AU - Li, Min AU - Meares, Claude F. AU - Salako, Qansy AU - Kukis, David L. AU - Zhong, Gao-Ren AU - Miers, Laird AU - DeNardo, Sally J. TI - Prelabeling of Chimeric Monoclonal Antibody L6 with <sup>90</sup>Yttrium- and <sup>111</sup>Indium-1,4,7,10-tetraazacyclododecane-<em>N,N′,N″,N‴</em>-tetraacetic acid (DOTA) Chelates for Radioimmunodiagnosis and Therapy DP - 1995 Dec 01 TA - Cancer Research PG - 5726s--5728s VI - 55 IP - 23 Supplement 4099 - http://cancerres.aacrjournals.org/content/55/23_Supplement/5726s.short 4100 - http://cancerres.aacrjournals.org/content/55/23_Supplement/5726s.full SO - Cancer Res1995 Dec 01; 55 AB - 90Y and 111In have been attached to chimeric monoclonal antibody L6 with a bifunctional chelating agent (DOTA-peptide isothiocyanate). The bifunctional chelating agent was prelabeled with either radiometal and then conjugated to the antibody. Studies in human patients showed excellent 111In single-photon emission computed tomography images of breast cancer lesions 24 h after injection. ©1995 American Association for Cancer Research.