PT  - JOURNAL ARTICLE
AU  - Cristaudo, Alfonso
AU  - Foddis, Rudy
AU  - Vivaldi, Agnese
AU  - Buselli, Rodolfo
AU  - Gattini, Vittorio
AU  - Guglielmi, Giovanni
AU  - Cosentino, Francesca
AU  - Ottenga, Franco
AU  - Ciancia, Eugenio
AU  - Libener, Roberta
AU  - Filiberti, Rosangela
AU  - Neri, Monica
AU  - Betta, PierGiacomo
AU  - Tognon, Mauro
AU  - Mutti, Luciano
AU  - Puntoni, Riccardo
TI  - SV40 Enhances the Risk of Malignant Mesothelioma among People Exposed to Asbestos: A Molecular Epidemiologic Case-Control Study
AID  - 10.1158/0008-5472.CAN-04-2219
DP  - 2005 Apr 15
TA  - Cancer Research
PG  - 3049--3052
VI  - 65
IP  - 8
4099  - http://cancerres.aacrjournals.org/content/65/8/3049.short
4100  - http://cancerres.aacrjournals.org/content/65/8/3049.full
SO  - Cancer Res2005 Apr 15; 65
AB  - We conducted a case-control study on asbestos exposure and presence of SV40 in tumor samples of malignant mesotheliomas (MMs) and bladder urotheliomas (BUs). PCR analysis revealed the presence of SV40 DNA (SV40+) in eight (42.1%) MMs and 6 (33.3%) BUs. The odds ratio for MM Asb− and SV40+ was 0.4 [95% confidence interval (95% CI), 0.03-4.0], for Asb+ and SV40− was 3.6 (95% CI, 0.6-21.0), and for Asb+ and SV40+ was 12.6 (95% CI, 1.2-133.9). Our results suggest that SV40 increases the risk of MM among individuals exposed to asbestos. ©2005 American Association for Cancer Research.