Table 2.

Endometrial tumors with coexisting p85α and p110α mutants

Case no.Histologyp85α mutantp110α mutanta
EECs
 T88EndometrioidR348XR88Qb, F667L
 T122EndometrioidK511VfsX2H1047Rb
 T132EndometrioiddelY463_L466M1004I
 T134EndometrioidE495XE545Kb, M1043Vb
NEECs
 T3SerousIntronicE81K
 T61Clear celldelT454_D464E453A
 T74SerousY334XH1047Yb, R93Q, K111Nb
 T77Clear cellR301XH1047Rb
 T79SerousR348XT1025A
 T113Clear cellS460KfsX5, D548GA222V, E365Kb
  • aFrom Rudd and colleagues (13).

  • bActivating mutants of p110α.