Table 1

Expression of COX-2 in 172 SCCs and in 27 ADCs of the esophagus as determined by immunohistochemistry

A. Percentage of positive tumor cells^a
	0	1	2	3	4
SCC	16	39	36	38	43
ADC	6	3	5	6	7
B.Staining intensity^b
	0	1+	2+
SCC	16	109	47
ADC	6	7	14
C.Immunoreactive score^c
	0	1	2	3	4	5	6	7	8
SCC	16	30	34	38	29	11	7	3	4
ADC	6	2	2	7	2	5	2	0	1

a Percentage of positive cells: 0, 0–4%; 1, 5–24%; 2, 25–49%; 3, 50–74%; 4, 75–100%.
b Staining intensity: 0, negative; 1+, weak; 2+, strong.
c Immunoreactive score: combination of ^a and ^b (see “Materials and Methods”).