Table 1

Immunophenotype of nonkeratinizing squamous metaplasias

Metaplastic lesionsCystectomyKeratin 19Keratin 7, 8, 18, and 20Keratin 14Keratin 10BG3C8 antigenKeratin 13Psoriasin
Type 1884-1Expressed by all cells in the epithelium; there were variations, however, in the staining intensity of the basal cell compartmentNegativeNegative or positive staining of the basal cell compartment, depending on the intensity of the keratin 19 staining of the basal cellsNegativeNegative or positive staining of the basal cell compartment, depending on the intensity of the keratin 19 staining of the basal cellsPositive staining, but basal cells were negative in areas with strong keratin 19 basal stainingPositive staining, suprabasal cells were stronger
864-1 (CIS type)Same as for 884-1NegativeBasal stainingSuprabasal stainingBasal stainingBasal and suprabasal stainingSame as for 884-1
Type 2884-1Expressed mainly in the basal cell compartmentNegativeBasal and suprabasal stainingSuprabasal stainingBasal and suprabasal stainingSuprabasal cells were positive, basal cells are negativePositive staining, suprabasal cells were stronger
864-1 (CIS type)Same as for 884-1NegativeBasal stainingSame as for 884-1Basal stainingBasal and suprabasal stainingSame as for 884-1
Type 3884-1NegativeNegativeBasal and suprabasal stainingSuprabasal stainingBasal and suprabasal stainingSuprabasal cells were weak, basal cells were negativePositive staining, suprabasal cells were stronger
864-1 (CIS type)NegativeNegativeSame as for 884-1Same as for 884-1Same as for 884-1Basal and suprabasal stainingSame as for 884-1