Table 1

p27Kip1 expression and clinicopathological parameters in 96 primary superficial bladder carcinomas

p27Kip1 expression
TotalHigh (%)Moderate (%)Low (%)Pa
Age (yr)
 ≥656224 (39%)10 (16%)28 (45%)
 <653415 (44%)9 (26%)10 (30%)0.26
Sex
 Male8333 (40%)16 (19%)34 (41%)
 Female136 (46%)3 (23%)4 (31%)0.78
Tumor grade
 Well differentiated133 (23%)6 (46%)4 (31%)
 Moderately differentiated5130 (59%)6 (12%)15 (29%)0.001b
 Poorly differentiated326 (19%)7 (22%)19 (59%)
Tumor stage
 A4221 (50%)8 (19%)13 (31%)
 15418 (33%)11 (20%)25 (47%)0.22a
p53 expressionc
 Positive (≥20%)5230 (58%)9 (17%)13 (25%)
 Negative (<20%)449 (20%)10 (23%)25 (57%)<0.001
  • a Statistical analyses were performed by the Pearson χ2 test. P < 0.05 was considered significant.

  • b The same values were also obtained when the Fisher’s exact test was used for the analysis.

  • c The values refer to the results obtained using the monoclonal Pab1801 antibody. See text for more details.