Table 1

Lung hydrophobic DNA adducts, smoking history, and age of female and male lung cancer patients

Females(mean ± SD)Males(mean ± SD)P(Wilcoxonrank test)
Adducts/108nucleotides
 Smokers15.39 ± 9.47 (n = 29)12.08 ± 8.14 (n = 93)0.047
 Nonsmokersa1.45 ± 0.65b (n = 13)4.10 ± 2.13a (n = 24)
Cigarettes/dayd13.3 ± 5.416.5 ± 7.40.057
Smoking yearsd33.9 ± 11.243.8 ± 10.09.5 × 10− 5
Pack-yearsd22.9 ± 12.435.0 ± 15.89.4 × 10− 5
Aged56.2 ± 13.462.2 ± 10.00.034
  • a Never-smokers and ex-smokers of 2 or more years of abstinence.

  • b Smoking versus nonsmoking females: P = 3 × 10−7.

  • c Smoking versus nonsmoking males: P = 4 × 10−8.

  • d Smokers.