Table 1

Synergistic effects by cotreatment with EC and other tea polyphenols on apoptosis, growth inhibition, and TNF-α release

Induction of apoptosisa (A415 nm)Growth inhibitionb (% of control)Inhibition of TNF-α releaseb IC50m)
Without ECWith EC (200 μm)Without ECWith EC (200 μm)Without ECWith EC (100 μm)
0.10 ± 0.0397.8>500c
EGCG (100 μmd)0.52 ± 0.220.98 ± 0.2873.327.86015e
ECG (50 μmd)0.27 ± 0.130.53 ± 0.1862.243.3307
EGC (200 μmd)0.14 ± 0.030.43 ± 0.08e100.072.2NDND
  • a Values represent the mean ± sd of two separate experiments performed in duplicate.

  • b Values are representative of two separate experiments performed in duplicate.

  • c IC50 of EC.

  • d Concentration for experiment on apoptosis and growth inhibition.

  • e P < 0.01.