Table 1

Effects of gemcitabine, HU, and Ara-C on KB-Gem clones

IC50a
Gemcitabine (μm)HU (mm)Ara-C (μm)
KB wild-type0.30 ± 0.060.43 ± 0.070.90 ± 0.11
KB-Gem32.30 ± 1.972.36 ± 0.3134.84 ± 11.7
HURS44.81 ± 1.3312.5 ± 1.3150.77 ± 13.7
  • a IC50 was determined as described in “Materials and Methods.” Values are means ± SD calculated from three separate experiments, each performed in duplicate.