Table 1

Development of tumors in cured mice

UV-2237mK-1735 M2
MiceaIncidenceTumor diameterIncidenceTumor diameter
Control10/1013.0 ± 3.010/1013.4 ± 3.1
Cured0/707/712.5 ± 2.5
  • a Normal control mice or mice in which primary tumors cured by intralesional injection of AdCIFN-β were maintained for 2 months and then challenged s.c. with 5 × 105/mouse of UV-2237m or K-1735 M2 cells. The mice were monitored once a week. The tumor incidence and diameter (mm) were recorded 4 weeks later. The data shown are from one representative experiment of two.