Table 2

Association between GSTP1 genotype and GST enzyme activity in normal esophageal mucosa from patients with Barrett’s epitheliuma

GSTP1 genotypeGST enzyme activity (nmol/min · mg protein)
GSTP1a-1a 914 ± 32 (n = 29)
GSTP1a-1b 817 ± 21 (n = 58)b
GSTP1b-1b 780 ± 37 (n = 11)b
  • a GSTP1 polymorphisms and GST enzyme activity were determined as described in “Materials and Methods.” GST enzyme activity is expressed as mean ± SE. Wilcoxon rank sum test was used to compare GST enzyme activity of the GSTP1a-1a subgroup with that in the GSTP1a-1b and GSTP1b-1b subgroups, respectively. n, number of patients in each group.

  • b P < 0.05 as compared to enzyme activity in the GSTP1a-1a subgroup.