Table 4

Model parameter estimates for a sample combined CO2/dThd study

ParameterSymbolUnitsNl brainaTumor
Blood volumeVbml/g0.0410.038
dThd blood-tissue transfer constant K 1t ml/min/g0.0160.047
dThd tissue volumeK1t/k2tml/g0.5601.450
DNA incorporation constant k 3t 1/min0.0150.008
dThd flux rate K dThd ml/min/g0.0060.009
CO2 blood-tissue transfer constant K 1c ml/min/g0.6400.530
CO2 tissue volumeK1c/k2cml/g0.6700.790
CO2 fixation constant k 3c 1/min0.0050.004
  • a N1, normal.