Table 1

Screening of CEA.Tg micea

Serum CEA (ng/ml)
GenotypeNo. of miceRT-PCRaNo. of miceRangeMean ± SE
CEA.Tg mice25+2512.8–133.060.8 ± 14.9
CEA-negative littermates25Negb10NegNeg
Wild-type B6 mice10Neg10NegNeg
  • a Individual mice were bled between 28–35 days. Approximately 100 μl of whole blood were used for PCR-based detection of the CEA transgene. Serum was collected from the remainder and tested for CEA levels as described in “Materials and Methods.”

  • b Neg, <5 ng CEA/ml serum.