Table 6

Geometric mean hormone levelsa among postmenopausal controls not using postmenopausal hormones by CYP17 genotypeb

HormoneControls (n)c
A1/A1 (n = 104)A1/A2 (n = 146)A2/A2 (n = 47)
Estrone sulfate (pg/ml)169.4 (96)148.5 (136)d164.5 (42)
Estrone (pg/ml)32.1 (102)31.2 (145)36.7 (46)d
Estradiol (pg/ml)8.0 (101)7.6 (145)9.1 (46)e
Testosterone (ng/dl)22.2 (100)21.6 (143)24.1 (44)
Androstenedione (ng/dl)63.0 (100)59.9 (142)73.8 (44)e
DHEA (ng/dl)227.4 (89)211.3 (132)260.1 (45)f
DHEAS (μg/dl)67.0 (99)70.8 (143)71.8 (46)
  • a Controlling for BMI, age, date of blood draw, time of blood draw, fasting status, and laboratory batch.

  • b The A1/A1 genotype is the reference group for all comparisons.

  • c Number varies due to missing data and removal of outliers.

  • d P ≤ 0.01.

  • e P ≤ 0.1.

  • f P ≤ 0.05.