Patient | Age^{a} (yr) | Gender | Operation^{b} | Site^{c} | Stage^{d} | Pixel counts^{e} |
---|---|---|---|---|---|---|
Immunized | ||||||
1 | 79 | F | 14 | Sigmoid | B | 395, 249, and 368 |
351, 412, and 565 | ||||||
2 | 76 | M | 14 | Sigmoid | A | 161, 192, and 265 |
349, 342, and 324 | ||||||
3 | 75 | M | 26 | Rectum | A | 175, 241, and 286 |
4 | 56 | M | 9 | Rectum | B | 766, 693, and 566 |
5 | 70 | M | 13 | Rectum | B | 64, 87, and 60 |
6 | 62 | F | 20 | Rectum | C | 206, 191, and 182 |
90, 196, and 82 | ||||||
7 | 87 | M | 20 | Cecum | B | 632, 523, and 451 |
8 | 82 | M | 11 | Cecum | C | 292, 289, and 222 |
Controls | ||||||
1 | 75 | F | Sigmoid | B | 217, 173, and 59 | |
167, 188, and 177 | ||||||
2 | 79 | M | Sigmoid | A | 262, 155, and 170 | |
182, 210, and 163 | ||||||
3 | 70 | M | Rectum | A | 152, 96, and 156 | |
4 | 60 | M | Rectum | B | 214, 262, and 222 | |
5 | 73 | M | Rectum | B | 53, 62, and 81 | |
6 | 65 | F | Rectum | C | 299, 221, and 300 | |
363, 356, and 204 | ||||||
7 | 81 | M | Cecum | B | 165, 177, and 176 | |
8 | 75 | M | Cecum | C | 87, 94, and 104 |
^{a} Age of patient at trial entry.
^{b} Time in days between immunization and tumor resection.
^{c} Site of primary tumor.
^{d} Dukes’ stage.
^{e} Mean pixel count for five areas of a tumor section stained with Apo2.7. The same regions of immunized and control tumors were paired and analyzed for significance by a two-tailed Wilcoxon signed rank test. Significantly (P < 0.005) more infiltration was seen in immunized tumors than in control tumors.