Table 2

Expression and mutational status of p63 and p53 in human bladder tumorsa

TAp63 expressionΔNp63 expressionp53 status
NormalAb.b LowNormalAb. HighNormalAbnormal
Specimen no.222517303017
TAp63 expression
Normal3 (17.6)19 (63.3)14 (46.7)8 (47.1)
Ab. Low14 (82.4)11 (36.7)16 (53.3)9 (52.9)
ΔNp63 expression
Normal3 (13.6)14 (56.0)11 (36.7)6 (35.3)
Ab. High19 (86.4)11 (44.0)19 (63.3)11 (64.7)
Low p21WAF17 (31.8)8 (32.0)6 (35.3)9 (30.0)4 (13.3)11 (64.7)
High MDM20 (0.0)1 (4.0)1 (5.9)0 (0.0)1 (3.3)0 (0.0)
Low 14-3-3ς4 (18.2)5 (20.0)4 (23.5)5 (16.7)3 (10.0)6 (20.0)
  • a Expression level of p63; less than half (<0.49; levels 0–2 for TAp63) and more than 2-fold (>0.38; levels 3–5 forΔ Np63) of means of normal tissues were classified as abnormal expression.

  • b Ab, abnormal.