Table 1

β-Catenin status and β-catenin accumulation

Sample No.Diameter of lesion (μm)No. of cryptsβ-Catenin mutation and amino acid substitutionβ-Catenin accumulation
CytoplasmNucleus
HACN
N11405++
N21204Codon 34 GGA(Gly)→GAA(Glu)++
N32607+++
N41809Codon 41 ACC(Thr)→ATC(Ile)+++
N528011Codon 28 CAA(Gln)→CAT(His)+
N6802Codon 32 GAT(Asp)→AAT(Asn)+
N72207Codon 34 GGA(Gly)→TGA(stop)+
N820010++
N91809Codon 32 GAT(Asp)→AAT(Asn)+
N103009++
N114209Codon 34 GGA(Gly)→GAA(Glu)++
N122407+
N131604Codon 34 GGA(Gly)→GAA(Glu)+++
N142208Codon 30 TAC(Tyr)→CAC(His)++
N152006Codon 32 GAT(Asp)→AAT(Asn)++
Codon 33 TCT(Ser)→TCG(Ser)
HACA
A14208
A22404Codon 35 ATC(Ile)→ACC(Thr)
A32807
A42607
A546010
A63408
A73006
A84008
A94005
A102405
A113809
A123206Codon 29 TCT(Ser)→TGT(Cys)
A132806
A143406
A151803Codon 32 GAT(Asp)→AAT(Asn)