Table 5

Relation between cigarette smoking and colorectal adenomas by GSTM1 polymorphism

Cigarette-yearsNon-nullNull
No.aORb (95% CI)No.aORb (95% CI)
019 /371.017 /361.1 (0.5–2.5)
1–39913 /221.2 (0.5–2.8)21 /251.7 (0.7–3.8)
400–79939 /272.9 (1.4–6.2)52 /531.9 (1.0–3.8)
800+26 /114.6 (1.8–11.4)18 /94.0 (1.5–10.7)
TrendcP = 0.0001P = 0.03
  • Number of cases/controls.

  • Adjusted for hospital, rank in the SDF, alcohol use, and body mass index.

  • Tested for each category of GSTM1 with ordinal scores 0, 1, 2, and 3 assigned to the four levels of cigarette-years.