Table 1

Clinical, histological, and CGH karyotype findings of 95 gastrointestinal stromal tumors obtained from 60 patients

Metastases from the same patient have the same number as the primary tumor but with a different letter, e.g. b, c, d.

No.Age/sex/codeHistologySiteaSizebFollow-up in monthsCGH karyotypea
LossesGains and high-level amplifications
159/m G1BenignJejunum5, 5NED, 511p, 15, 18, 22
245/m G2BenignStomach4, 5NED, 4514
350/m G12BenignStomach3, 3NED, 381p, 148q
475/m G25BenignStomach3NED, 8714, 22
563/m G9BenignStomach3, 5NED, 4114q11–q13, 14q23–qter, 22
661/f G10BenignStomach7NED, 401p, 14
781/m G13BenignStomach5, 5NED, 11015
880/m G14BenignStomach5NED, 12414
99/73/f G18BenignStomach3, 5NED, 8111p, 145q22–qter
1063/f G19BenignJejunum2NED, 311p, 11, 14, 15, 211q, 5, 7p, 18q
1158/m G21BenignStomach4NED, 21014q13–qter, 22
1249/f G23BenignStomach16NED, 20922q12–qter
1365/f G24BenignStomach3NED, 2814, Xq
1473/m G26BenignStomach2NED, 8214, 15, 21, 22
1579/f G29BenignStomach2NED, 13322q12–qter
1678/m G32BenignStomach2, 5NED, 7514, 22
1780/m G35BenignJejunum4, 5NED, 241p, 6q, 13q21–qter, 1419
1885/m G38BenignStomach5NED, 2114, 22
1969/m G41BenignJejunum2NED, 141p, 11p, 13, 14q11–q12, 15, 22
2067/f G44BenignStomach9NED, 614
2153/m G48BenignStomach6NED, 3114
2234/m G49BenignStomach6, 5NED, 327, 8, 11
2341/m G52BenignJejunum7NED, 131p31.2–pter, 6q, 22
2468/m G60BenignStomach2NED, 3314
2574/f G15MalignantStomachNANA14q13–qter, 15q15–qter, 1816, 17
2660/f G22MalignantStomach4NA10q3q, 5, 7, 12, 13, 18
2759/m G47MalignantColon18NED, 121p, 6q, 8p22–pter, 10, 11q14–qter, 12, 14, 15, 18q11–q232q22–qter
2852/m G6MalignantStomach15DOD, 53cen–p21, 141q32–qter, 3p22–pter, 3q (3q26–q29) 8p12–qter
2972/m G17MalignantJejunum15NA2q31–qter, 3p, 9p
3060/m G20MalignantJejunum10DOD, 91p, 13, 14cen–q23, 15, 21, 223q, 8, 16p, 17
3168/f G27MalignantStomach15DOD, 711cen–p31, 3p, 14q21–q23, 15q21–qter2q34–q37
3288/f G31MalignantStomach6DOD, 261cen–p31, 8p, 9q, 10p15–q22, 22, X1p32–pter, 5p, 9p, 17q21–q25
3363/m G36MalignantColon16NED, 248p21–pter, 10pter–q22, 14q21–q321p, 5, 7p, 8q22–qter, 9q, 19, 20
3463/m G11MalignantRectum7NED, 398p, 9, 13q21–qter, 14, 15q15–q22, 223, 5, 8q, 11, 12, 17, 18, X
3586/f G16MalignantSmall intestine6, 5DOD, 191p, 2p, 15
3643/f G28MalignantJejunum8NED, 781cen–p31, 13q21–qter, 15q15–qter, 18q4, 17, 18p, 19
3769/m G30MalignantStomach11DOD, 3211q14–q22, 19, X
3841/m G42MalignantStomach18NED, 121p, 2p13–pter, 9p, 14, 15, 2211q
3944/m G43MalignantStomach17NED, 9225, 7
4073/f G45MalignantStomach4NED, 85, 6p, 7
4171/f G46MalignantJejunum9NED, 271p, 4, 10, 15, 22
4273/f G50MalignantJejunum9Alive, 91p, 2q, 9p, 13, 14, 15, 18q, 225p14–pter
4359/m G58MalignantStomach12NED, 279, 144p, 5, 7
4437/f PR28MalignantSmall intestineNADOD, 501p, 8p, 9p, 11p, 14, 18q, 221q11–q31, 8q, 9q, 16q, 19p, 20q
4573/f G65MalignantDuodenum6, 5NED, 241p, 6q21–qter, 9p, 11, 13, 14, 157
4646/f K1MalignantStomach10Alive, 357p15–p22, 7q32–qter, 9p21.2–pter, 14, 15, 18p, 22q132q, 4q, 8q23–qter
46bK2MetastasesOmentum7p15–p22, 7q32–qter, 9p21.2–pter, 13q13–qter, 14, 15, 19q13.2–qter, 22q132q, 6p, 8q23–qter, 17q
46cK3MetastasesColon mesentry7p15–pter, 7q32–qter, 9p21.2–pter, 14, 15, 19q13.2–qter, 22q132q, 4q, 8q23–qter, 17q
46dK4MetastasesOmentum4p, 7p15–p22, 7q32–qter, 9p21.2–pter, 10, 11, 13q13–qter, 14, 15, 19q13.2–qter, 22q13 8q23–qter, 17q
46eK5MetastasesLiver4p, 7p15–p22, 7q32–qter, 9p21.2–pter, 11p, 13q13–qter, 14, 15, 19q13.2–qter, 22q132q, 8q23–qter, 17q
46fK6MetastasesLiver1p34.3–pter, 4, 6q14–qter, 7p15–p22, 7q32–qter, 9, 14, 18, 22q131q, 5
46gK7MetastasesColon mesentry7p15–p22, 7q32–qter, 9p21.2–pter, 14, 15, 18p, 19q13.2–qter, 22q132q, 4q, 8q23–qter, 17q
46hK8MetastasesColon mesentry7p15–p22, 7q32–qter, 9p21.2–pter, 13q13–qter, 14, 15, 19q13.2–qter, 22q132pter–q13, 4q, 8q22–qter, 17q
46lK9MetastasesColon mesentry1p, 7p15–p22, 7q32–qter, 9p21.2–pter, 11, 13q, 14, 15, 19q13.2–qter, 22q13, X2q, 4q, 8q22–qter (8q23–qter), 17q
46jK10MetastasesColon mesentry7p15–p22, 7q32–qter, 9p21.2–pter, 13q13–qter, 14, 15, 19q13.2–qter, 22q132pter–q13, 4q, 8q22–qter, 17q
46kK11MetastasesOvary7p15–p22, 7q32–qter, 9p21.2–pter, 11, 13, 14, 15, 19q13.2–qter, 22q13, X2q, 4q, 8q22–qter, 17q
46lK12MetastasesColon mesentry7p15–p22, 7q32–qter, 9p21.2–pter, 13q13–qter, 14, 15, 19q13.2–qter, 22q132pter–q13, 8q23–qter, 17q
46mK14MetastasesColon mesentry6q14–qter, 7p11–p15, 7q32–qter, 9pter–q34.1, 14, X
4767/m PR1MalignantJejunum7DOD, 351p, 2, 11, 13, 14, 15, 18
47bPR2MetastasesAbdomen1p, 2, 11, 13, 14, 151q, 3, 5, 6p, 7, 8, 9
47cPR48MetastasesAbdomen1p, 2, 11, 13, 14, 15, 181q11–q24, 3p14–p22, 6p, 7, 8
47dPR3MetastasesAbdomen1p, 2p22–pter, 11, 13, 14, 15, 181q, 3, 6p, 7, 8, 9
4844/m G8MalignantStomach17NA1q32–qter, 148q22–qter
48bPR5MetastasesAbdomen1p, 2q, 5p14.3–pter, 12q15–qter, 14, 19q8
4964/m PR6MalignantSmall intestine12Alive, 241p, 6q, 13, 14, 15, 18, 225p, 6p, 7, 12q
49bPR7MetastasesLiver1p, 6q, 13, 14, 15, 18, 225p, 6p, 7, 12q
5059/f PR8MalignantStomach15Alive, 969pter–q31, 10p, 13, 14, 19q13.3–qter, X2p14–pter, 4p15–pter, 6p, 8, 9q32–qter, 10q, 12, 17q, 19pter–q13.2, 20q
50bPR9MetastasesLiver9pter–q31, 10p, 13, 14, 19q13.3–qter, X2p14–pter, 7, 8, 12, 17, 19pter–q13.2, 20q