Table 1

Subset of genes transiently induced by doxorubicin in MCF-7 cells that intersects with genes overexpressed in the doxorubicin-resistant MCF-7/D40 cells

NameAccession numberFold changes in gene expression 15 h after exposure of MCF-7 to doxorubicinFold changes in gene expression in MCF/D40 cells
Cell cycle genes
CDC28 kinase 1L29222−7.3−2.3
XRCC1 M360899.87.6
Protein CDC27AA4890985.95.5
Neuronal genes
Ataxin 2U70323−7.7−2.8
Human neuronal apoptosis inhibitory proteinU192514.63.7
SynaptotagminM55047/J0571014.010.4
Signal transduction genes
Fms-related protein tyrosine kinaseD0013323.09.5
GranulinM7516117.111.6
RecoverinAB0018385.17.6
Transferrin receptor proteinM115077.44.6
Collapsin response mediator protein 1U1727820.713.5
Transcription factors
RNA polymerase IIL37127−7.8−2.0
Sigma 3BX9945927.516.4
Metabolic genes
Cellular retinoic acid binding proteinM6886729.417.0
Epoxide hydrolaseJ0351815.811.3
Ubiquitin-proteasome
26S proteasome regulatory subunit 4AA62290518.611.6
Protein secretion
PescadilloU7831011.98.8