Table 2

Summary of bak sequence alterations in gastric and colorectal cancers

TumorStageaExonCodonSequence changesPredicted effect
Gastric cancers
GC4TAdvanced369AGC→GGCSer→Gly
GC10TAdvanced6188ATC→ACCIle→Thr
GC12TAdvanced214TGC→TGTSilent
GC21TAdvanced6203TTT→TCTPhe→Ser
Colorectal cancers
CRC7TAdvanced25CAA→CTAGln→Leu
CRC12TAdvanced6188ATC→ACCIle→Thr
CRC15TAdvanced214TGC→TGTSilent
CRC19TAdvanced26GGC→GGTSilent
  • a Gastric and colorectal cancers were staged by the tumor-node-metastasis (TNM) system (early stage, stage I; advanced stage, stage II and III).