SI and CNRs for tumor regions
Region of interest | SI mean ± SD (AU) | CNR | P |
---|---|---|---|
CaD+, periphery | 59,100 ± 1,500 | NA | |
CaD+, center | 52,600 ± 1,500 | NA | |
CaD−, tumor | 35,300 ± 5,200 | NA | |
Nontarget tissuea | 23,000 ± 1,700 | NA | |
CaD+ periphery to CaD− | NAb | 8.6 | <0.001 |
CaD+ center to CaD− | NA | 6.0 | <0.005 |
CaD+ periphery to background | NA | 22.8 | <0.001 |
CaD+ center to background | NA | 16.2 | <0.001 |
a
Observed NIRF signal
originates from endogenous fluorochromes (autofluorescence) and
exogenous (i.e., diet) fluorochromes. CNR =
(SI1 − SI2)/
.
b NA, not applicable.