Table 1

Chromosome 3p LOH and distribution of sex and age in neoplastic and nonneoplastic nasopharyngeal tissues from high-risk and low-risk regions for NPC

Normal NPaNPCc
Case no.GenderAge3p LOHbCase no.GenderAge3p LOHb
High-risk region
Hong Kong (southern Chinese)S-NP1F27+S-NPC1M45+
S-NP2M41S-NPC2M35+
S-NP3F11+S-NPC3M45+
S-NP4F17+S-NPC4M35+
S-NP5M15+S-NPC5F73+
S-NP6F16+S-NPC6M35+
S-NP7M19+S-NPC7M70+
S-NP8F26S-NPC8M43+
S-NP9M44+S-NPC9M31+
S-NP10M38+S-NPC10M50+
S-NP11F33+S-NPC11M41+
S-NP12M39S-NPC12M65+
S-NP13M55+S-NPC13M36+
S-NP14F79S-NPC14F71+
S-NP15M79+S-NPC15M43+
S-NP16M68S-NPC16M66+
S-NP17F42+S-NPC17F51+
S-NP18M94+S-NPC18M69+
S-NP19M85+S-NPC19M52+
S-NP20M46+S-NPC20M69+
S-NP21M69+S-NPC21M44+
S-NP22M41
S-NP23F72+
M:F, 14:9Mean, 45.917/23 (73.9%)M:F, 18:3Mean, 50.921/21 (100%)
Low-risk region
Anhui/BeijingN-NP1M28N-NPC1M47+
(northern Chinese)N-NP2M50N-NPC2M67+
N-NP3F30N-NPC3M40+
N-NP4F36+N-NPC4M53+
N-NP5M46N-NPC5M35+
N-NP6F34N-NPC6M39+
N-NP7M34+N-NPC7F50+
N-NP8M18N-NPC8M25
N-NP9M11N-NPC9M60+
N-NP10M42N-NPC10M58
N-NP11M76N-NPC11M62+
N-NP12M54N-NPC12M56+
N-NP13M53+
N-NP14M55
N-NP15M45
N-NP16M54
Toronto CanadaC-NP1F76C-NPC1M37+
(Caucasians)C-NP2M66C-NPC2M74+
C-NP3F69C-NPC3M63+
C-NP4M55+C-NPC4M59+
C-NP5F68C-NPC5M48+
C-NP6F64C-NPC6M55+
C-NP7F61C-NPC7F66+
C-NP8M80C-NPC8F54
C-NP9F57C-NPC9M35
C-NP10M31
C-NP11M41+
C-NP12F27
C-NP13F67+
C-NP14F42
M:F, 18:12Mean, 496/30 (20%)M:F, 18:3Mean, 51.617/21 (81%)
  • a High-risk region, n = 23; Low-risk region, n = 30.

  • b +, LOH on at least one microsatellite marker on chromosome 3p; −, no LOH at all informative loci on chromosome 3p.

  • c High-risk region, n = 21; Low-risk region, n = 21.