Table 2

The association of LOH on chromosome 3p and presence of EBER transcripts in the neoplastic and nonneoplastic nasopharyneal samples from high- and low-risk regions of NPC

High-risk regionLow-risk regions
Southern Chinese (Hong Kong)Total of all regionsCentral/Northern Chinese (Anhui/Beijing)Caucasians (Toronto, Canada)
3p LOHEBER3p LOHEBER3p LOHEBER3p LOHEBER
NPC100% (21/21)100% (21/21)81% (17/21)90.5% (19/21)83.3% (10/12)100% (12/12)77.8% (7/9)77.8% (7/9)
Normal NPa73.9% (17/23)0% (0/23)20% (6/30)0% (0/30)18.8% (3/16)0% (0/16)21.4% (3/14)0% (0/14)
Fetal NP0% (0/10)0% (0/10)NANANANANANA
Dysplastic NP (Total)75.0% (6/8)50.0% (4/8)NANANANANANA
High-grade75.0% (3/4)100% (4/4)
Low-grade75.0% (3/4)0% (0/4)
  • a NP, histologically normal nasopharyngeal epithelia; NA, not available.