Table 1

Selected characteristics of 240 women treated for breast cancer, by GSTP1 Ile105Val genotype

All subjects (%)GSTP1 codon 105 genotype
Ile/Ile (%)Ile/Val (%)Val/Val (%)
Total24011010723
Age at diagnosis
≤3926 (10.8)13 (11.8)10 (9.4)3 (13.0)
40–4982 (34.2)35 (31.8)36 (33.6)11 (47.8)
50–5971 (29.6)36 (32.7)32 (29.9)3 (13.0)
60–6942 (17.5)19 (17.3)18 (16.8)5 (21.7)
70+19 (7.9)7 (6.4)11 (10.3)1 (4.4)
Race
Caucasian192 (80.0)93 (84.6)80 (74.8)19 (82.6)
African-American48 (20.0)17 (15.5)27 (25.2)4 (17.4)
Stage
I65 (27.1)32 (29.1)27 (25.2)6 (26.1)
II, node negative48 (20.0)19 (17.3)23 (21.5)6 (26.1)
II, node positive73 (30.4)38 (34.6)29 (27.1)6 (26.1)
III41 (17.1)18 (16.4)19 (17.8)4 (17.4)
IV13 (5.4)3 (2.7)9 (8.4)1 (4.4)
Estrogen receptor status
Positive147 (61.3)62 (56.4)71 (66.4)14 (60.9)
Negative93 (38.8)48 (43.6)36 (33.6)9 (39.1)
Progesterone receptor status
Positive111 (46.3)49 (44.6)54 (50.5)8 (34.8)
Negative129 (53.8)61 (55.5)53 (49.5)15 (65.2)