Table 1

Variant UGT1A1 alleles analyzed in this studya

AlleleNucleotide changeEffect on proteinExon
UGT1A1*28(TA)7TAAReduced expressionPromoter
UGT1A1*6211G→AG71R1
UGT1A1*27686C→AP229Q1
UGT1A1*291099C→GR367G4
UGT1A1*71456T→GY486D5
  • a The most common (wild-type) UGT1A1 allele is regarded as UGT1A1

  • * 1.