Table 2

Baseline characteristics of patients

Leukopenia (grade 4) and/or diarrhea (grade 3 or worse)a
Experienced (n = 26)Not experienced (n = 92)P
Gender (men/women)14/1266/260.085b
Median age (range, yr)60 (38–76)61 (41–75)>0.2c
Performance status>0.2b
08 (31%)31 (34%)
115 (58%)51 (55%)
≥23 (12%)10 (11%)
Primary disease>0.2b
Small cell lung4 (15%)17 (18%)
Non-small cell lung16 (62%)49 (53%)
Colorectal3 (12%)18 (20%)
Other3 (12%)8 (9%)
Distant metastases21 (81%)68 (74%)>0.2b
Previous treatment>0.2b
None12 (46%)36 (39%)
Systemic chemotherapy12 (46%)47 (51%)
Surgery8 (31%)34 (37%)
Radiotherapy3 (12%)17 (18%)
Complications>0.2b
Diabetes2 (8%)8 (9%)
Liver diseases3 (12%)6 (7%)
  • a Japan Society for Cancer Therapy criteria.

  • b χ2 test.

  • c Mann-Whitney U test.