Table 1

Characteristics of the human breast cancer cell lines

Cell lineER status (24)Tumorigenic potential (29)p53 status (2223)ras mutation (28)Others
HBL 100 (30)Wild type
T47 D++ (with estrogen)Single allele Mutant
MDA 468++MutantNRaEGF-R+ (25) PTEN− (27)
SKBr 3++Mutantc-erbB2+ (26)
MDA 231+++Mutant+
MDA 435+++ (metastases)Mutant
  • a NR, not reported; EGF-R, epidermal growth factor receptor.