Table 1

Patient data and tissue content of ATP, lactate, and glucose in carcinoma of the human uterine cervix in patients with no clinically detectable metastases, and patients with diagnosed metastases

PatientRecurrenceFIGOaSurvivalKIMetabolite concentrationsb (μmol/g)
ATPLactateGlucose
Nonmetastatic tumors (nm)
nm 1YesIVaNo1001.1 ± 0.52.7 ± 1.74.8 ± 1.5
nm 2NoIIIbYes1000.4 ± 0.32.9 ± 1.23.5 ± 0.6
nm 3NoIIbYes1000.4 ± 0.23.7 ± 2.32.2 ± 1.3
nm 4NoIIbYes1000.4 ± 0.33.9 ± 3.13.3 ± 2.1
nm 5NoIIbYes1000.9 ± 0.94.7 ± 2.93.7 ± 1.8
nm 6YesIIbNo1001.0 ± 0.75.0 ± 2.81.7 ± 0.6
nm 7NoIIbYes801.0 ± 0.75.1 ± 3.21.9 ± 1.0
nm 8YesIIbNo1001.6 ± 0.66.4 ± 4.11.3 ± 0.7
nm 9NoIIbYes1001.4 ± 1.06.7 ± 4.31.9 ± 0.7
nm 10NoIbYes1000.8 ± 0.47.2 ± 4.21.6 ± 0.9
nm 11YesIIbNo800.6 ± 0.69.0 ± 5.30.7 ± 0.4
nm 12NoIIbYes1001.6 ± 0.99.2 ± 5.91.4 ± 1.0
nm 13YesIIIbNo1000.4 ± 0.310.7 ± 5.91.0 ± 0.7
nm 14NoIIaYes1000.4 ± 0.211.2 ± 5.84.4 ± 0.7
Total (mean± SD)0.9 ± 0.46.3 ± 2.8c2.4 ± 1.3
Range0.4–1.6 2.7–11.20.7–4.8
Metastatic tumors (m)
m 1NoIIIbYes900.7 ± 0.85.4 ± 3.32.2 ± 1.2
m 2YesIIbYes1001.1 ± 0.65.7 ± 3.61.7 ± 0.9
m 3NoIIbYes1000.6 ± 0.46.9 ± 4.84.0 ± 2.6
m 4YesIIbNo1002.2 ± 1.37.3 ± 3.31.6 ± 1.1
m 5YesIIbNo1000.4 ± 0.27.4 ± 4.12.7 ± 1.5
m 6YesIIbNo907.4 ± 4.12.3 ± 1.4
m 7YesIIbNo1000.5 ± 0.47.8 ± 3.62.5 ± 0.6
m 8YesIIIbNo800.5 ± 0.68.8 ± 5.11.8 ± 0.9
m 9YesIIbNo1001.2 ± 0.68.8 ± 4.83.0 ± 1.0
m 10YesIIbNo800.2 ± 0.039.5 ± 4.51.5 ± 0.9
m 11YesIIIbYes800.9 ± 0.911.2 ± 4.72.7 ± 1.5
m 12YesIIIbNo700.4 ± 0.311.2 ± 5.11.4 ± 0.8
m 13YesIIbNo1001.1 ± 0.711.6 ± 5.04.4 ± 1.9
m 14YesIIbNo1001.3 ± 0.611.8 ± 5.53.1 ± 1.2
m 15YesIIbNo901.0 ± 0.412.3 ± 5.41.2 ± 0.7
m 16YesIVaNo1000.6 ± 0.412.4 ± 5.81.1 ± 1.0
m 17NoIIbYes1000.6 ± 0.412.5 ± 5.12.1 ± 1.0
m 18YesIIIbNo901.2 ± 0.512.8 ± 5.50.5 ± 0.3
m 19YesIIIbNo1000.5 ± 0.413.7 ± 8.91.5 ± 0.8
m 20YesIIIbNo901.2 ± 0.615.6 ± 8.03.8 ± 1.8
Total (mean± SD)0.8 ± 0.510.0 ± 2.92.2 ± 1.0
Range0.2–2.2 5.4–15.60.5–4.4
  • a FIGO, Fédération Internationale des Gynaecologistes et Obstetristes; KI, Karnofsky’s index.

  • b Mean ± SD.

  • c P = 0.001.