Methylation of multiple genes in pancreatic cancers and normal pancreatic tissue
| Samples | na | p16 | RARĪ² | CACNA1G | TIMP3 | THBS1 | hMLH1 | E-cad | DAPK | MGMT | MINT1 | MINT2 | MINT31 | MINT32 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pancreatic carcinomasb | 36 | 14% | 11% | 11% | 11% | 6% | 6% | 3% | 0% | 0% | 33% | 8% | 28% | 67% |
| Pancreatic cell lines | 9 | 33% | 56% | 33% | 11% | 11% | 0% | 22% | 11% | 0% | 56% | 22% | 78% | 100% |
| Total | 45 | 18% | 20% | 16% | 11% | 7% | 4% | 7% | 2% | 0% | 38% | 11% | 38% | 73% |
| Normal pancreata | 14 | 0% | 0% | 0% | 0% | 0% | 0% | 36% | 21% | 0% | 0% | 14% | 0% | 0% |
a n, number examined.
b Thirty-five pancreatic cancer xenografts and 1 primary carcinoma.