Table 1

Methylation of multiple genes in pancreatic cancers and normal pancreatic tissue

Samplesna p16RARĪ²CACNA1GTIMP3THBS1hMLH1E-cadDAPKMGMTMINT1MINT2MINT31MINT32
Pancreatic carcinomasb3614%11%11%11%6%6%3%0%0%33%8%28%67%
Pancreatic cell lines933%56%33%11%11%0%22%11%0%56%22%78%100%
Total4518%20%16%11%7%4%7%2%0%38%11%38%73%
Normal pancreata140%0%0%0%0%0%36%21%0%0%14%0%0%
  • a n, number examined.

  • b Thirty-five pancreatic cancer xenografts and 1 primary carcinoma.