Table 1

Presence of CD8+ T cells within esophageal tumors decreases with tumor progression

Levels of CD8+ T cells were estimated in 70 patients after complete resection of primary esophageal carcinomas as described in “Materials and Methods.” Statistic analysis was performed using the χ2 test. Statistical significance was set at P < 0.05. Data in parentheses are percentages.
CD8+ T cells
Total primary tumors (70 cases)No. of casesi.t.p.t.SC/nilP
pT Stagea0.008
 pT1134 (31)7 (54)2 (15)
 pT2237 (30)4 (17)12 (52)
 pT3280 (0)9 (32)19 (68)
 pT450 (0)1 (20)4 (80)
Lymph node metastasisa0.015
 pN0237 (30)7 (30)9 (40)
 pN+474 (8)15 (32)28 (60)
Tumor gradinga0.040
 Low63 (50)2 (33)1 (17)
 Moderate273 (11)9 (33)15 (56)
 High375 (13)11 (30)21 (57)
Histotype0.112
 Adenocarcinoma378 (22)8 (22)21 (56)
 SCC333 (9)14 (43)16 (48)
  • a Classified according to Tumor-Node-Metastasis classification. pT, tumor size; pN, lymph node involvement.