Time-to recurrence and time-to death dates in esophageal cancer patients depend on localization and amount of CD8+ T cells within the tumors
| Presence of i.t., p.t., or SC or no CD8+ T cells in 70 primary carcinomas of the esophagus was compared to clinical follow-up. Median time to recurrence and median time to death dates are listed. Data in parentheses are ranges. As a control follow-up data for nodal negative (pN0) vs nodal positive patients (pN+) are also shown. | |||||||
|---|---|---|---|---|---|---|---|
| No. of Patients | Time to recurrence (mo) | Recurrence (no.) | Log rank | Time to death (mo) | Death (no.) | Log rank | |
| CD8+ i.t. | 11 | – | 0 | – | 0 | ||
| CD8+ p.t. | 22 | 20 (7–32) | 13 | 0.0003 | 50 (10–89) | 9 | 0.0004 |
| CD8+ SC/0 | 37 | 16 (12–20) | 25 | 18 (10–25) | 21 | ||
| pN0a | 23 | 44 (35–55) | 6 | 45 (37–51) | 5 | ||
| pN+ | 47 | 16 (13–18) | 32 | 0.0004 | 33 (23–44) | 25 | 0.0029 |
a Classified according to Tumor-Node-Metastasis classification.