Associations between MSI as determined by the panel of 12 markers and reproductive factors
OR (referent)a | OR (95% CI) | OR (95% CI) | OR (95% CI) | P trend | |
---|---|---|---|---|---|
Number of pregnancies | None | 1–2 | 3–4 | 5+ | |
MSI+/MSI−/control no. | 24/41/93 | 26/147/288 | 53/210/416 | 43/145/323 | |
MSI+ vs. control | 1.0 | 0.4 (0.2–0.7) | 0.5 (0.3–0.9) | 0.5 (0.3–0.9) | 0.36 |
MSI− vs. control | 1.0 | 1.2 (0.8–1.8) | 1.2 (0.8–1.7) | 1.0 (0.7–1.6) | 0.68 |
MSI+ vs. MSI− | 1.0 | 0.3 (0.2–0.6) | 0.4 (0.2–0.7) | 0.5 (0.3–0.9) | 0.63 |
Total ovulatory months | <294 | 294–369 | 370–430 | 431+ | |
MSI+/MSI−/control no. | 14/92/196 | 35/124/257 | 41/156/309 | 49/144/302 | |
MSI+ vs. control | 1.0 | 1.8 (0.9–3.5) | 1.8 (0.9–3.3) | 2.2 (1.2–4.1) | 0.12 |
MSI− vs. control | 1.0 | 1.1 (0.8–1.5) | 1.1 (0.8–1.5) | 1.1 (0.8–1.5) | 0.89 |
MSI+ vs. MSI− | 1.0 | 1.7 (0.9–3.4) | 1.5 (0.8–3.0) | 2.1 (1.1–4.0) | 0.14 |
a Adjusted for age and energy intake.