Table 1

Clinicopathological features of endometria by PTEN immunohistochemistry and slide diagnosis

% PTEN-null by diagnosis (fraction)
ProliferativePersistent proliferativeEINTotal
Sample
 Curettage42.9 (6/14)54.5 (6/11)75.0 (6/8)54.5 (18/33)
 Biopsy42.9 (18/42)56.7 (17/30)59.3 (16/27)51.5 (51/99)
Clinical indication
 Bleeding42.9 (12/28)56.3 (18/32)55.0 (11/20)51.3 (41/80)
 Infertility/recurrent abortion41.7 (5/12)0.0 (0/0)100.0 (1/1)46.2 (6/13)
 Prior hyperplasia0.0 (0/1)0.0 (0/0)71.4 (5/7)75.0 (6/8)
 Anatomic (fibroids, septum, polyp, thick stripe)50.0 (3/6)100.0 (1/1)100.0 (1/1)62.5 (5/8)
 Other (pain, endometriosis)20 (1/5)33.3 (1/3)0.0 (0/2)20.0 (2/10)
 Unspecified75.0 (3/4)60.0 (3/5)100 (4/4)76.9 (10/13)
Hormones
 Endogenous42.9 (24/56)55.9 (19/34)64.3 (18/28)51.7 (61/118)
 Exogenous0.0 (0/0)57.1 (4/7)57.1 (4/7)57.1 (8/14)
Menopause
 Pre42.9 (24/56)57.1 (20/35)66.7 (14/21)51.8 (58/112)
 Post0.00 (0/0)50.0 (3/6)57.1 (8/14)55.0 (11/20)
Total42.9 (24/56)56.1 (23/41)62.9 (22/35)52.3 (69/132)