Table 1

Joint genotype distribution of the S/L polymorphism at amino acid 217 and the A/T polymorphism at position 541 in a random sample of 257 unrelated prostate cancer cases and 355 healthy unrelated controls

The joint genotype distribution for the cases was obtained by sampling at random one brother from each sibship. The reported number for each genotype (rounded to the nearest integer) is the mean based, on 1000 realizations of the sampling procedure. Genotypic proportions are given in parentheses.
Residue 217Residue 541
CasesControls
AAATTTAAATTT
SS 120 (0.467)190 (0.535)
SL 93 (0.362)21 (0.082)124 (0.349)10 (0.028)
LL 19 (0.074)4 (0.016)28 (0.079)1 (0.003)2 (0.006)
Allele frequency:―L = 0.3113―L = 0.2761
―T = 0.0486―T = 0.0211