Table 1

Side effects of viral therapy

Gal4aHrR3KOS
Skin lesionsb0/8c0/88/8
Weight loss0/80/85/8
Neurological deficitsd0/80/84/8
  • a Gal4 represents the replication-defective HSV injected into tumor; hrR3 represents the replication-conditional virus; KOS represents wild-type virus.

  • b Necrotic skin sores.

  • c Number of affected animals/total number of treated animals.

  • d Manifested as hind limb paresis.