Table 1

Genotype distributions at the polyglutamine repeat polymorphism in AIB1 in 448 women who carry germ-line BRCA1 or BRCA2 mutations

Polyglutamine repeat lengthCases (%)Controls (%)
20/281 (0.4%)0 (0%)
22/282 (0.7%)0 (0%)
22/290 (0%)1 (0.6%)
25/262 (0.7%)0 (0%)
26/266 (2.2%)3 (1.8%)
26/2825 (9.0%)20 (11.8%)
26/2929 (10.4%)29 (17.1%)
26/300 (0%)1 (0.6%)
26/310 (0%)1 (0.6%)
27/291 (0.4%)0 (0%)
-----------------------------------------------------------------------------------------Cutpoint <28a
28/2832 (11.5%)27 (15.9%)
28/29107 (38.5%)67 (39.4%)
28/301 (0.4%)0 (0%)
28/310 (0%)1 (0.6%)
-----------------------------------------------------------------------------------------Cutpoint <29a
29/2971 (25.5%)20 (11.8%)
29/301 (0.4%)0 (0%)
Total278170
  • a Denotes cutpoints used in the analyses presented in Tables 2 <$REFLINK> and 3 <$REFLINK> .