Table 1

Combination treatment with CV706 and radiation

DaybFTV relative to untreated controlsa
CV706IrradiationCombination treatmentRatio of expected FTV/observed FTVd
ExpectedcObserved
70.90700.77520.70310.48061.46
140.79100.75370.59620.32801.82
210.74190.66450.49300.24522.01
280.51440.54810.28190.16831.66
350.46670.47620.22220.09052.46
420.39430.48370.19070.02856.69
  • a FTV (mean tumor volume experimental)/(mean tumor volume control).

  • b Day after tumors treated with agents.

  • c (mean FTV of CV706) × (mean FTV of radiation).

  • d Obtained by dividing the expected FTV by the observed FTV. A ratio of >1 indicates a synergistic effect, and a ratio of <1 indicates a less than additive effect.