Table 1

Tetramer-guided analysis of the TCR BV chain usage of MAGE-A10254–262-specific cells

LAU 50 PaLAU 50/22LAU 50/15LAU 155 PaLAU 155/6D1LAU 119 PaLAU 203/1B8LAU 169/4E8LAU 42 PaLAU 42/2D6HD 591 PaHD 795 PaHD 795/4D11HD 795/2B6
BV-specific mAb
1<0.01b<0.01<0.01<0.01<0.01<0.01<0.01<0.0163100<0.01<0.01<0.01<0.01
13.1<0.01<0.01<0.01<0.01<0.01<0.01<0.01<0.0130<0.01<0.01<0.01<0.01<0.01
17<0.01<0.01<0.01<0.01<0.01<0.01<0.01<0.01<0.01<0.01<0.0143100<0.01
21.30.8<0.01100100100<0.01<0.01<0.01<0.01<0.0121.7<0.01<0.01<0.01
2298100<0.01<0.01<0.01100<0.01100<0.01<0.01329.1<0.01<0.01
% repertoire covered98.81001009353.752.1
  • a P, polyclonal. The others are CTL clones obtained by limiting dilution culture.

  • b Number represents percentage of positive cells within the A2/MAGE-A10254–262 tetramer+ CD8+ T-cell fraction.