Table 1

Cannabinoid receptor expression in human astrocytomas of different malignancya

ReceptorExpressionGrades I–II (n = 12)Grade III (n = 11)Grade IV (n = 14)
CB1Negative6 (50%)8 (73%)8 (57%)
Moderate2 (12%)1 (9%)3 (22%)
High/very high4 (33%)2 (18%)3 (22%)
CB2Negative6 (50%)5 (45%)4 (29%)
Moderate3 (25%)2 (18%)1 (7%)
High/very high3 (25%)4 (36%)9 (64%)b
  • a Receptor immunoreactivity was evaluated as absent (negative staining) or present (moderate or high/very high staining) in biopsies from human astrocytomas of low (grades I–II) and high (grades III–IV) malignancy. The percentage of cases is shown in parentheses.

  • b Significantly different (P < 0.01) from values of CB2 receptor high/very high expression in low malignancy and grade III tumors and from values of CB1 receptor high/very high expression in grade IV tumors.