Table 1

p53 mutation frequencies in nontumorous peripheral lung tissue in lung cancer cases and normal controls

SamplesMut. freq.a × 10 codon 157 (GTC to TTC)Mut. freq. × 10 codon 249 (AGG to AGT)Mut. freq. × 10 codon 249 (AGG to ATG)Mut. freq. × 10 codon 250 (CCC to ACC)Sex/ageSmoking status (pack-yr)Cotinine (ng/ml)
Normal controls
CC0.4NDNDNDM /41N/A308
L0NDNDNDF /45N/A245
W0NDNDNDM /44N/A414
Z0.1NDNDNDF /36N/A260
B0.1NDNDNDM /22N/A431
E0.2NDNDNDF /1N/A1
F0.5NDNDNDM /31N/A1
X0.6NDNDNDM /32N/A1
Nontumorous lung from cancer patients
25722.418.60NDM /5320N/A
2675.46.806.8M /5353N/A
22726.216.816NDM /6936N/A
17910.72018.1NDM /6542N/A
2214.81617.1NDM /7645N/A
2317.69.77.8NDF /5740N/A
2553.67.90NDM /7125N/A
2610.900NDF /6830N/A
2795.200NDF /5714N/A
3032.300NDM /6128N/A
3090.200NDM /7431N/A
3171.000NDM /6420N/A
3190.200NDM /4937N/A
3231.000NDM /4123N/A
  • a Mut. freq., mutation frequency; ND, not detected; N/A, not available.