Table 3

DC vaccine, immune responses, and clinical outcome

Pt. I.D.aDC vaccineImmune responsesClinical outcome
Dose × 106/kgCD1a+CD14−/CD1a±CD14+ mean % of positive cellsControl antigensMelanoma antigensEarly evaluation at 10 wk
FLUKLHn>2 Ag
10.14 /25YesYes4YesNP
20.16 /28YesYes2NoPD
40.17 /38YesYes4YesNP
60.16 /42YesYes1NoPD
190.110 /40YesYes2NoNE
30.255 /44NoNo0NoPD
50.2517 /20YesYes4YesNP
90.259 /32YesYes4YesNP
160.257 /25YesYes4YesPD
80.514 /33YesYes3YesNP
100.511 /42YesYes3YesNP
130.510 /36NoNo0NoPD
170.58 /27YesYes4YesNP
121.013 /24YesYes3YesNP
151.010 /52YesYes1NoPD
181.011 /20NDYes2NoNP
201.012 /19YesYes1NoPD
211.08 /30YesYes3YesNP
  • a Pt. I.D., patient identification; Ag, antigen; NP, •••; NE, •••.