Table 3

A subset of the 193 genes expressed at higher levels in grade I tumors compared with grade IV tumors, listed by category

Ratios of levels in grade (Gr.) I versus Gr. II, Gr. IV, or normal brain tissue (N.B.) and the P that was computed from a one-way ANOVA model are provided.
GenBank Acc. no.Gene symbolGene descriptionGr. I: Gr. IVGr. I: Gr. IIGr. I: N.B.
RatioPRatioPRatioP
Lipid metabolism
 M15856 LPL Lipoprotein lipase4.30.0001.50.82816.20.000
Carrier proteins
 J02611 APOD Apolipoprotein D2.80.0001.50.1972.30.143
Transcription/translation regulation
 X63741 EGR3 Early growth response 33.30.0082.60.1970.70.046
 Z19002 ZNF145 Zinc finger protein 145 (Kruppel-like)2.70.0001.90.0981.50.277
 V01512 FOS v-fos FBJ murine osteosarcoma viral oncogene homolog2.10.0052.90.0103.20.011
 M99436 TLE2 Transducin-like enhancer of split 22.10.0032.10.0002.10.008
 M92843 ZFP36 Zinc finger protein homologous to Zfp-36 in mouse2.10.0062.70.0102.60.015
 D43638 CBFA2T1 Core-binding factor, runt domain, α subunit 22.00.0040.60.0240.50.023
 U68019 MADH3 Smad32.00.0012.00.0421.90.048
Receptors and signal transduction
 U33447 GPR17 G protein-coupled receptor 174.80.0004.80.0304.80.059
 S76475 NTRK3 Neurotrophic tyrosine kinase, receptor, type 33.90.0001.60.2061.40.468
 U16306 CSPG2 Chondroitin sulfate proteoglycan 2 (versican)3.10.0002.10.03420.50.000
 L20971 PDE4B Phosphodiesterase 4B, cAMP-specific3.10.0003.20.0063.70.001
 L14542 KLRC3 Killer cell lectin-like receptor subfamily C, member 33.00.0011.80.4673.40.000
 U46744 DTNA Dystrobrevin, α2.90.0012.70.0462.50.117
 L20814 GRIA2 Glutamate receptor, ionotropic, AMPA 22.80.0000.80.3730.80.276
 U02566 TYRO3 TYRO3 protein tyrosine kinase2.60.0012.00.2221.10.660
 M84349 CD59 CD59 antigen2.50.0001.60.0053.50.000
 X54867 KLRC1 Killer cell lectin-like receptor subfamily C, member 12.30.0022.10.1583.60.000
 L13738 ACK1 Activated p21cdc42Hs kinase2.30.0001.00.5651.70.171
 M90657 TM4SF1 Transmembrane 4 superfamily member 12.20.0062.20.0012.20.000
 U18934 TYRO3 TYRO3 protein tyrosine kinase2.20.0011.50.3550.90.396
 X75756 PRKCM Protein kinase C, μ2.20.0001.70.0153.40.000
 Y10032 SGK Serum/glucocorticoid regulated kinase2.10.0011.90.0301.40.108
 U59877 RAB31 RAB31, member RAS oncogene family2.10.0011.90.1445.00.000
 X64878 OXTR Oxytocin receptor2.10.0002.30.0093.40.000
 M61906 PIK3R1 Phosphoinositide-3-kinase, regulatory subunit2.00.0010.80.3551.10.952
 M34181 PRKACB Protein kinase, cAMP-dependent, catalytic, β2.00.0001.10.8310.50.002
Protein degradation regulation
 M17783 PN1 Nexin, glia-derived2.90.0002.00.1083.40.002
 U76456 TIMP4 Tissue inhibitor of metalloproteinase 42.30.0003.40.00212.40.000
 M13690 C1NH Complement component 1 inhibitor2.20.0013.60.0007.70.000
 D87258 PRSS11 Protease, serine, 112.10.0002.10.0313.30.000
Cytokine
 M69203 SCYA4 Small inducible cytokine A44.90.0004.80.0682.60.130
 M23178 SCYA3 Small inducible cytokine A33.80.0003.10.1542.60.104
 X04500 IL1B Interleukin 1, β2.30.0024.10.0091.60.231
ECM or ECM-associated proteins
 X54412 COL9A1 Collagen, type IX, α15.60.0003.40.0079.20.007
 X73608 SPOCK Testican4.40.0002.30.0401.80.453
 X96753 CSPG4 Chondroitin sulfate proteoglycan 44.30.0015.90.0235.90.000
 L41162 COL9A3 Collagen, type IX, α33.10.0002.50.0203.90.014
 X58079 S100A1 S100 calcium-binding protein A12.50.0011.60.6521.20.693
 U65932 ECM1 ECM protein 12.10.0013.90.0024.60.000
 Z19585 THBS4 Thrombospondin 42.10.0048.00.00711.40.000
Stress response proteins
 X68277 DUSP1 Dual specificity phosphatase 12.10.0003.00.0022.80.006
Amyloid related
 U46901 SNCA Synuclein, α (non A4 component of amyloid precursor)2.00.0000.70.4740.20.000
Cytoskeleton
 D31883 ABLIM Actin-binding LIM protein2.40.0001.40.2832.00.009
 M77016 TMOD Tropomodulin2.10.0021.60.1753.50.005
Cell adhesion/aggregation
 U96769 CHAD Chondroadherin8.00.0008.00.0128.00.001
 M55172 AGC1 Aggrecan 12.70.0002.70.0442.70.001
 U52840 SEMA5A Semaphorin 5A2.70.0002.80.0106.40.000
 L10373 TM4SF2 Transmembrane 4 superfamily member 22.60.0001.10.9920.80.539
 U79251 OPCML Opioid-binding protein/cell adhesion molecule-like2.50.0001.80.1391.40.497
 X16841 NCAM1 Neural cell adhesion molecule 12.40.0001.30.3631.30.245
 U52100 EMP2 Epithelial membrane protein 22.00.0002.50.0014.00.000