Table 3

Transcripts most elevated in adenomas and cancersa

Tag sequenceNormalAdenomasCancersTranscript name
NC-1NC-2AD-A1AD-B2Tu-98Tu-102
ATGTAAAAAA 0 0 26 32 2 12 Lysozyme (LYS)
TAATTTTTGC 0 1 99 12 20 37 Differentially expressed in hematopoietic lineages (DEHL)
GTGTGTTTGT 0 0 17 29 17 15 Transforming growth factor β-induced (TGFBI)
GTGCTCATTC 0 0 13 7 2 10 Macrophage-inhibitory cytokine, 1 (MIC-1)
TTCCAGCTGC007629Adaptor-related protein complex 2, α 2 subunitb
ACCATTGGAT0031039Interferon-induced transmembrane protein 1 (9–27)b
TTTCCACTAA 0 0 8 4 4 6 Regenerating islet-derived 1 α (REGA)
CAAGGACCAG 0 0 5 6 10 12 Renal dipeptidase (RDP)
AGGACCATCG0082118Defensin, α 5, Paneth cell-specificc
  • a These tags displayed at least 20-fold elevation in both neoplastic states. The numbers given are the raw tag counts for each tag observed in each library. Transcript name provides a description of matching UniGene cluster (Build 3/13/01). Rows shown in bold are genes confirmed by quantitative PCR to be differentially expressed.

  • b Differential expression could not be confirmed by quantitative PCR, suggesting that the tag was derived from a different transcript than the one indicated.

  • c Not tested.