Clinical outcome for the FLT3WT/WT, FLT3ITD/WT, and FLT3ITD/− genotype groups
FLT3WT/WT (N = 59) | FLT3ITD/WT (N = 15) | FLT3ITD/− (N = 8) | P | |
---|---|---|---|---|
Percentage of CR | 86 | 79 | 75 | 0.70 |
DFS | ||||
Median (months) | 52a | 24 | 4 | |
Percentage of DFS at 12 months (95% confidence interval) | 71 (62, 80) | 51 (35, 66) | 17 (12, 22) | 0.0017 |
Survival | ||||
Median (months) | 46a | 46a | 7 | |
Percentage alive at 12 months (95% confidence interval) | 74 (65, 82) | 65 (48, 81) | 13 (10, 15) | 0.0014 |
a Nonparametric estimate of the median is not available. Tabled value represents the median assuming the survival estimates after the last observation follows an exponential curve.