Impact on clinical outcome of the absence of WT FLT3
| FLT3WT/WT and FLT3ITD/WT (N = 74) | FLT3ITD/− (N = 8) | P | |
|---|---|---|---|
| Clinical outcome | |||
| Percentage of CR | 85 | 75 | 0.61 |
| DFS | |||
| Median (months) | 44a | 4 | |
| Percentage of DFS at 12 months (95% confidence interval) | 68 (59, 76) | 17 (12, 22) | 0.0005 |
| Survival | |||
| Median (months) | 47a | 7 | |
| Percentage alive at 12 months (95% confidence interval) | 72 (64, 79) | 13 (10, 15) | 0.0003 |
a Nonparametric estimate of the median is not available. Tabled value represents the median assuming the survival estimates after the last observation follows an exponential curve.