Table 1

Summary of surface TRAIL-R2 expression, caspase-3 activation, and apoptosis induced by TRAIL in melanoma cell linesa

Cell lines% TRAIL-R2% Activated caspase-3% Apoptosis
Mel-CV7275.6 (12.4)54
Mel-RM59.665.37 (6.6)76
Mel-FH57.262.3 (2.9)24
Me440588.486.5 (8.4)61
MM20076.174.2 (7.2)83
Me100710.417.39 (1.8)0
SK-Mel-2818.618.8 (2.2)20
Mel-RMu50.667.7 (4.9)15
IgR379.971.2 (4.1)21
Mel-LT63.450.1 (2.01)15
Mel-AT40.28.4 (1.6)0
Me1053809.2 (1.1)0
  • a Values indicate the percentage of positive cells. Values in parentheses indicate the mean fluorescence intensity.