Table 1

The expression of the components of DNA-PK in normal human colon

Ku70Ku86PKcs
ColonocytesNuclearCytoplasmicbCytoplasmic
Crypt
 Entire crypt74%52%43%
 Lumenal one-thirda22%48%57%
 Basal two-thirdsa4%0%0%
Positive cells
 All48%058%
 60–90%35%30%30%
 <60%17%70%13%
  • a Only or predominantly in this segment.

  • b 1/3 staining was both nuclear and cytoplasmic.