Table 3

Pharmacokinetic parameter values of parent BMS-275291 in C57BL/6 mice

Dose (mg/kg)Cmax (ng/ml)Tmax (h)AUC, 24 h (ng┬Ěh/ml)
MaleFemaleMaleFemaleMaleFemale
307228340.50.5440582
9021943222870.50.51755518102